Bruce Lab
Laboratory of developmental biology and genomics (A. Bruce)
LAB SUMMARY
Research under my supervision in the 'Laboratory of Developmental Biology and Genomics (LDB&G)' is focussed on understanding the molecular mechanisms that underpin the pre-implantation stages of mammalian embryo development, using the mouse embryo as our model system. Specifically, we address when and how do cells of the developing embryo first begin to differ from each other and how does this impact on the derivation of the three cell lineages present at the time of implantation at the late blastocyst stage? To address these questions we employ both 'classical' embryological techniques and 'cutting edge' molecular biology based approaches. We also collaborate with our colleagues to provide 'genomics' based tools for the study of insect model organisms.
Please also visit the webpages of the lab's co-head: RNDr Alena Krejčí relating to Notch signalling in Drosophila melanogaster.
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LAB NEWS
Vasanth Thamodaran of the Bruce lab wins the 2011 Department of Molecular Biology's Image Competition with his image of a mouse morula. Congratulations to him from the rest of the lab! - 2011 Department of Molecular Biology's Image Entrants Gallery
Department
Photogallery