Kotsyfakis Lab

Laboratory of genomics and proteomics of disease vectors (M. Kotsyfakis)

The research activity of our group focuses on:

  • Applying genomic and proteomic methodologies to discover salivary or midgut effectors that determine arthropod vectorial capacity.
  • Vertebrate proteolytic cascades that are regulated by arthropod salivary secretion in the sites of disease vector infestation, facilitating blood meal uptake by the vector and/or pathogen transmission.
  • Demonstrating the pharmacological action of arthropod salivary proteins in the vertebrate host (hemostasis, vascular biology, immunomodulation) and their potential for the treatment of human diseases (cancer, multiple sclerosis, allergic asthma) using transgenic animals and animal models for human diseases.

 

 

Kotsyfakis Lab

 

Detail


People

List of people of Laboratory: Kotsyfakis Lab

Detail


Publications

List of publications of Laboratory: Kotsyfakis Lab

Detail