Kotsyfakis Lab
Laboratory of genomics and proteomics of disease vectors (M. Kotsyfakis)
Our research activity focuses on
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applying genomic and proteomic technologies in order to uncover salivary or midgut effectors that contribute to arthropod vectorial capacity.
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vertebrate proteolytic cascades that are regulated by arthropod salivary secretion in the sites of disease vector infestation, facilitating blood meal uptake and/or pathogen transmission.
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demonstrating the pharmaceutical action of arthropod salivary proteins in the vertebrate host (hemostasis, vascular biology, immunomodulation) and their potential in the treatment of human diseases (cancer, multiple sclerosis) using knock-out animals and disease animal models.
Department
Photogallery