Sauman Lab

Laboratory of molecular chronobiology (I. Sauman)

 

Flies expressing GFP in eyesCircadian biological clocks are found in most living organisms and their fundamental properties are highly conserved in vertebrates and invertebrates. The fruitfly, Drosophila melanogaster served as a premier insect species for the molecular analysis of the circadian rhythms. Because of the functional similarities of the circadian clocks among all metazoans, it was suggested that the molecular mechanisms underlying the clock function would be conserved as well. Surprisingly, we have found striking differences between the molecular regulations of the circadian timing system even among holometabolous insects. The long-term goal of our laboratory is to gain a better understanding of the cellular and molecular mechanisms that underlie circadian rhythmicity.

 

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