Publications

Publikace vydané v rámci Katedry molekulární biologie

List of publications of Laboratory: Bruce Lab

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  • Mihajlovic AI and Bruce AW (2016). Rho-associated protein kinase regulates subcellular localisation of Angiomotin and Hippo-signalling during preimplantation mouse embryo development. Reprod. Biomed. Online 33, 381-390.

  • Thamodaran V and Bruce AW. p38 (Mapk14/11) occupies a regulatory mode governing entry into primitive endoderm differentiation during preimplanation mouse embryo development. Open Biology, rsob.160190

  • Mihajlovic AI, Thamodaran T, and Bruce AW. (2015). The first two cell-fate decisions of mouse embryo development are not functionally independent. Sci. Rep. 5, 15034

  • Dhami P*, Saffrey P*, Bruce AW*, Dillon SC*, Chiang K, Bonhoure N, Koch CM, Bye J, James K, Foad NS, Ellis PD, Watkins NA, Ouwehand WH, Langford CF, Andrews RM, Dunham I and Vetrie D (2010). Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution. PLoS ONE 5(8): e12339. *equal contribution

  • Jedrusik A, Bruce AW*, Tan MH*, Leong DE, Skamagki M, Yao M and Zernicka-Goetz M (2010). Maternally and zygotically provided Cdx2 have novel and critical roles for the early development of the mouse embryo. Dev. Biol. 344, 66-78. *equal contribution

  • Dhami P, Bruce AW, Jim JH, Dillon SC, Hall A, Cooper JL, Bonhoure N, Chiang K, Ellis PD, Langford CF, Andrews RM and Vetrie D. (2010). Genomic approaches uncover increasing complexities in the regulatory landscape at the human SCL (TAL) locus. PLoS ONE 5(2), e9059.

  • Wu Q*, Bruce AW*, Jedrusik A, Ellis PD, Andrews RM, Langford CF, Glover DM and Zernicka-Goetz M. (2009). CARM1 is required in ES cells to maintain pluripotency and resist differentiation. Stem Cells 27, 2637-2645. *equal contribution.

  • Zernicka-Goetz M, Morris SA and Bruce AW (2009). Making a firm decision: Transcriptional regulation of cell fate in preimplantation development. Nat Rev. Genet. 10, 467-477.

  • Bruce AW, Lopez-Contreras AJ, Flicek P, Down T, Down T, Dhami P, Dillon SC, Koch CM, Langford CF, Dunham I, Andews RM and Vetrie D. (2009). Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level. Genome Res. 19, 994-1005.

  • The ENCODE Project Consortium - including Bruce AW (2007). Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 477, 799-816.

  • Koch CM, Andrews RM, Flicek P, Dillon SC, Karaoz U, Clelland GK, Wilcox S, Beare DM, Fowler JC, Couttet P, James KD, Lefebvre GC, Bruce AW, Dovey OM, Ellis PD, Dhami P, Langford CF, Weng Z, Birney E, Carter NP, Vetrie D and Dunham I. (2007). The landscape of histone modifications across 1% of the human genome in five human cell lines. Genome Res. 17, 691-707.

  • Johnson RJ, Gamblin RJ, Ooi L, Bruce AW, Donaldson IJ, Westhead DR, Wood IC, Jackson RM and Buckley NJ. (2006). Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication. Nucleic Acids Res. 34, 3862-3877.

  • Bruce AW, Krejci A, Ooi L, Deuchars J, Wood IC, Dolezal V and Buckley NJ. (2006). The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype. J. Neurochem. 98, 1828-1840.

  • Follows GA, Dhami P, Gottgens B, Bruce AW, Campbell PJ, Dillon SC, Smith AM, Koch C, Donaldson IJ, Scott MA, Dunham I, Janes ME, Vetrie D and Green AR. (2006). Identifying gene regulatory elements by genomic microarraying mapping of DNAseI hypersensitive sites. Genome Res. 16, 1310-1319.

  • Bruce AW*, Donaldson IJ*, Wood IC, Yerbury SA, Chapman M, Sadowski MI, Gottgens B and Buckley NJ. (2004). Whole genome analysis of Repressor Element-1 Silencing Transcription factor (REST) binding sites reveals novel target genes. Proc. Natl. Acad. Sci. USA 101, 10458-10463. *equal contribution.

  • Krejci A, Bruce AW, Tucek S, Dolezal V and Buckley NJ. (2004). Multiple promoters drive cell-specific expression of the human M2 muscarinic acetylcholine gene. J. Neurochem. 91, 88-98.

  • Belyaev ND, Wood IC, Bruce AW, Street M, Trinh JB and Buckely NJ. (2004). Distinct RE1 Silencing Transcription Factor (REST)-containing complexes interact with different target genes. J. Biol. Chem. 279, 556-561.

  • Wood IC, Belyaev ND, Bruce AW, Jones C, Mistry M, Roopra A and Buckley NJ. (2003). Interaction of the repressor element 1-silencing transcription factor, (REST), with target genes. J. Mol. Biol. 334, 863-874.